How far is it from Raleigh, NC to Charleston, SC? Looking for ideas for more destinations within driving distance of Charleston? MapQuest Driving Directions to Raleigh, NC. The driving distance between Charleston, SC and Raleigh, NC is approximately 280 miles. Raleigh, NC and Charleston, SC are in the same time zone (EDT). Compare the flight distance to driving distance from Charleston, SC to Raleigh, NC.Calculate the total cost to drive from Charleston, SC to Raleigh, NC.Or find out if it's better to fly or drive from Charleston, SC to Raleigh, NC? Help. Find out how many hours from Charleston to Raleigh by car if you're planning a road trip. Or get a full Raleigh to Charleston flight plan. Try searching for places within 4 hours of Charleston. The halfway point is Quinby, SC. The default drive score from Raleigh to Charleston is 142. I like to know the best route to drive to Charleston from Raleigh NC. You can also compare the travel time if you're flying or driving by calculating the distance from Raleigh to Charleston. Driving distance from Raleigh, NC to Charleston, SC is 279 miles (450 km). Estimated flight time is 54 minutes. Compare the flight distance to driving distance from Raleigh, NC to Charleston, SC.Calculate the total cost to drive from Raleigh, NC to Charleston, SC.Or find out if it's better to fly or drive from Raleigh, NC to Charleston, SC? Flight distance from Raleigh to Charleston (Raleigh–Durham International Airport – Charleston International Airport) is 217 miles / 350 kilometers / 189 nautical miles. flight distance = 220 miles It's a 04 hours 21 minutes drive by car. This is the fastest route from Raleigh, NC to Charleston, SC. There are 220.23 miles from Charleston to Raleigh in northeast direction and 279 miles (449.01 kilometers) by car, following the I-95 N route.. Charleston and Raleigh are 4 hours 15 mins far apart, if you drive non-stop .. suggestions please? The distance by car is 447 km. Driving distance from Raleigh (RDU) to Charleston (CHS) is 270 miles / 434 kilometers and travel time by car is about 4 hours 51 minutes. Would going towards the coast then taking HWY17 to Charleston good or just take the middle route on I90 or what ever that middle road is? Try searching for places within 4 hours of Raleigh. You can also compare the travel time if you're flying or driving by calculating the distance from Charleston to Raleigh. The halfway point is Quinby, SC. Follow the Raleigh to Charleston driving route along I-95 S. Get driving directions from Raleigh to Charleston . Driving Directions to Raleigh, NC including road conditions, live traffic updates, and reviews of local businesses along the way. Charleston, SC and Raleigh, NC are in the same time zone (EDT). Or get a full Charleston to Raleigh flight plan. Legal. Flight distance is approximately 220 miles (354 km) and flight time from Raleigh, NC to Charleston, SC is 26 minutes.Don't forget to check out our "Gas cost calculator" option. So in this case, it's better to drive from Raleigh to Charleston. These results are based on the actual driving distance from Raleigh to Charleston, which is 278 miles or 447 kilometers. Answer 1 of 9: Good evening. Find out how many hours from Raleigh to Charleston by car if you're planning a road trip. As far as things to see between Raleigh and Charleston the simple answer is you'll see lots of pine trees, but that's not very helpful.. As far as sights to see, there really isn't much of anything worth stopping to see along I-95 in southern North Carolina or the Pee Dee of South Carolina.As mentioned by another poster you could stop at South of the Border, if you like cheesy tourist shops. 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